CRISPR-Cas9 System in S. Thermophilus

A virus with an unknown A virus with a known genome attacks the cell genome attacks the

The viral genome is deactivated , OO, &; \ U x \

CRISPR RNA guides cas-9 protein to break up viral DNA at the target sequence

A portion of the

viral DNA sequence C)

is copied to create a The target sequence in the

new spacer viral genome recognized by CRISPR RNA

New spacer is inserted between

CRISPR sequences The bacterium is now immune CRISPR al