CRISPR-Cas9 System in S. Thermophilus

Avirus with an unknown Avirus with a known genome attacks the cell genome attacks the,

cell

The viral genome 55 ; deactivated \ U > oO Se

CRISPR RNA guides cas-9 protein to break up viral DNA at the target sequence

A portion of the

viral DNA sequence ()

is copied to create a The target sequence in the

new spacer viral genome recognized by CRISPR RNA

New spacer is inserted between CRISPR sequen

omen: