Induced Pluripotent Stem Cells from Mouse Embryonic Fibroblasts

Retrovirus RNA Kp with mouse DNA RNA-DNA hybrid Possible Cell Differentiations (-20 um) Mouse embryo Mouse embryonic eYf & fibroblasts —_——_ Ly (differentiated cells, 15 ym) Neural cells Va Muscle cells

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Retroviruses with selected Fibroblasts become induced Cartilage’cells RNA alter the genome in pluripotent stem cells Retroviruses the fibroblasts. (undifferentiated cells). (100 nm) foro jo! [o}ofo }o}

Epithelial cells