Publication of the Division of Public Health Services January/February 2004, Vol. 18, No. 1 Inf luenza Strains Providers, Public Health System by Karen Lewis, MD Bacterial pathogens such as information on influenza activity in Streptococcus pneumoniae, Arizona or nationally, please visit the Haemophilus influenzae, or group A website for ADHS at www.hs.state. beta-hemolytic streptoccus can cause az.us/phs/oids/epi/flu/ or for CDC at pneumonia even without influenza. www.cdc.gov/flu/weekly/index.htm However, the incidence of S. aureus As of this writing, several hunas a cause for pneumodred cases of influenza nia is three times more from 12 counties had So, when a patient common when associbeen laboratory-conwith influenza-like ated with influenza (1). firmed by either rapid symptoms has Physicians are seetesting or viral culture. worsening respiratory ing more patients with The percentage of visits distress, consider a community-acquired for influenza-like illnessbacterial pneumonia, MRSA infections. es at sentinel providers around the state order cultures, and Therefore, it is not increased steadily from start broad-spectrum surprising to find MRSA complicating influenza. the week ending antibiotics pending Since S. aureus pneuNovember 15 through culture results. monia can have a fulthe week ending minant course, the December 19. At least choice of empiric antibiotics is very three influenza-associated deaths important. So, when a patient with among children had also been influenza-like symptoms has worsenconfirmed. ing respiratory distress, consider a bacterial pneumonia, order cultures, Bacterial infections and start broad-spectrum antibiotics complicating influenza pending culture results. Several deaths have occurred this Empiric antibiotics that would year in the United States due to cover MRSA, S. pneumoniae, H. pneumonia from the combination of influenzae, and group A betainfluenza and methicillin-resistant hemolytic streptococcus would be Staphylococcus aureus (MRSA). Vancomycin and a third generation Respiratory morbidity and mortality cephalosporin (like ceftriaxone/ from influenza can be due to either Rocephin® or cefotaxime/Claforan®). viral pneumonia, or a secondary bacterial pneumonia. Influenza came in with a bang this winter. However, if we are fortunate, the influenza outbreak in Arizona will have started to wane by the time you read this article. This season may or may not turn out to be much worse than usual, but there are a few things healthcare providers should be aware of this year. The first laboratory-confirmed influenza case of the season in Arizona was identified in midOctober, much earlier than during four of the previous five seasons. Influenza was reported as “widespread” in Arizona for the week ending December 6, 2003. Nationally, the influenza season also had an early start, with 24 states reporting widespread activity by the end of the first week in December. The predominant influenza strain nationally is A/Fujian (H3N2), a drift variant of the A/Panama (H3N2) strain included in this year’s vaccine. Both A/Fujian and A/Panama strains have been identified from Arizona isolates. All influenza specimens subtyped by the Arizona State Health Laboratory as of December 10 were influenza A(H3N2). Data change quickly during an influenza season, so the statewide picture may look very different by the time of publication. For current continued on page 2 Visit the ADHS Web site at www.hs.state.az.us New CDC Guidelines on SARS Page 2 January/February 2004 Earn CME Credits for Public Health Lectures Page 3 Substance Abuse Treatment Page 4 Communicable Disease Summary Page 6 HIV and AIDS in the State of Arizona Page 7 New Comm. Disease Rules Published Page 8 Prevention Bulletin 1 Inf luenza continued from page 1 Oral antibiotics that often cover MRSA include trimethoprim-sulfamethoxazole (although it gives poor S. pneumoniae coverage), clindamycin, or linezolid/Zyvox®. (Note: Linezolid should only be used in extraordinary cases, where the infection is known to be due to a multiply resistant organism such as MRSA, and effective antibiotics such as TMPSMZ and clindamycin are contraindicated.) Some physicians in Arizona have been seeing many patients who test positive for both influenza and group A beta-hemolytic streptococcus. Please remember to consider the possibility of secondary bacterial infections in patients with influenza. Influenza vaccine supply Manufacturers produced 85.5 million doses of inactivated influenza vaccine for the U.S. for the 2003-2004 influenza season. This was expected to be adequate for the demand. For example, 79 million doses of vaccine were sold in the U.S. for the 2002-2003 influenza season (2). However, demand increased due to widely publicized illnesses and pediatric deaths. The Arizona supply of inactivated influenza vaccine was mostly gone by the middle of December; however, Federal resources were mobilized to send more vaccine into the states for highrisk groups. Plan for next year Influenza vaccination not only protects high-risk individuals. It also decreases influenza in health care workers (who spread influenza to their patients) (3), decreases morbidity associated with day care spread of influenza (4), and decreases work absenteeism in health adults by 43% (5). Start planning now to get ready for next year’s influenza outbreak! Karen Lewis, MD, is an infectious disease specialist with the Arizona Department of Health Services. She can be reached at 602.364.3289 or klewis@hs.state.az.us. References: 1. Treanor JJ. “Influenza Virus.” Principles and Practice of Infectious Diseases. Mandell GL, Bennett JE, Dolin R. Churchill Livingston, Philadelphia; 2000,1823-1849. 2. http://www.naccho.org/general825.cfm 3. Carman WF, Elder AG, Wallace LA et al. Effects of influenza vaccination of health-care workers on mortality of elderly people in long-term care: a randomized controlled trial. Lancet 2000; 355: 93-97. 4. Hurwitz ES, Haber M, Chang A, et al. JAMA 2000; 284: 1677-1682. 5.Nichol KL, Lind A, Margolis KL, et al. The effectiveness of vaccination against influenza in healthy, working adults. NEJM 1995; 333: 889-893. 2 Prevention Bulletin New CDC Guidelines on SARS By Bob England, MD The CDC has published guidelines to quickly detect and contain SARS, even in the absence of known SARS anywhere in the world, at www.cdc.gov/ncidod/sars/ updatedguidance.htm. The major points for health care providers and institutions are: Promote “respiratory hygiene.” This is a bigger deal than one might think. It means providing masks in every waiting room and encouraging those with a cough to use them. It means providing alcohol-based hand sanitizer in convenient locations in waiting rooms, so that patients can use it after handling tissues and so forth. It means teaching patients to use these and teaching front desk staff to encourage their use. During colds and flu season, we should see a large fraction of those in the waiting room and elsewhere wearing masks. Ask three questions of every patient hospitalized with pneumonia without a known underlying etiology. Have they, within 10 days of symptom onset: • Had a history of recent travel to mainland China, Hong Kong, or Taiwan, or had close contact with ill persons with a history of recent travel to such areas? or; • Been employed in an occupation at particular risk for SARS-CoV exposure? (This includes any healthcare worker with direct patient contact or a worker in a laboratory that contains live SARS-CoV.) or; • Been part of a cluster of cases of atypical pneumonia without an alternative diagnosis? (i.e., ask whether they’ve been around anyone else with pneumonia.) If you get a yes answer to any of the above, REPORT the case to your local health department. (Also, let us know as soon as an alternative etiology is discovered). If SARS does return, guidelines still in draft form may ratchet this up to include the same questions and reporting of any patient with a fever or respiratory symptoms. That’s potentially a lot of patients. continued on page 3 January/February 2004 Noteworthy Earn CME Credits for Public Health Lectures Are you interested in learning more about SARS? Influenza? Smallpox? Other emerging infections? The Arizona Department of Health Services’ Office of Emergency Preparedness and Response offers one hour lectures through the Public Health Emergency Preparedness and Response Lecture series. The lectures include the following subjects: SARS; Influenza; West Nile Virus; Category A agents of Bioterrorism; Smallpox; and Respiratory Illness: Is It Viral, Bacterial, or Bioterrorism? Each lecture is designated to provide up to one hour of category one credit of CME. Lectures will be given by Dr. Peter Kelly and Dr. Karen Lewis. The lecturers will bring the lectures to you, and are available to groups of doctors throughout the state. Call 602.364.3289 for more information and to schedule lectures. Providers Urged to Report Varicella Cases As the use of varicella vaccine causes further decline in chickenpox cases, there will be greater opportunity for real control of this once common disease. In addition, we need an accurate baseline count of adult cases of varicella in order to monitor the effect of the vaccine on the vaccinated population as it ages. To do this, the public health system needs good surveillance. The Arizona Department of Health Services encourages the reporting of all varicella cases, especially those among adults. All varicella should be reported to the local health department by the January/February 2004 health care provider as per the Arizona Administrative Code (A.A.C. R9-6-301). This year, the Department is also implementing the Arizona School-based Chickenpox Surveillance System for reporting of chickenpox by select schools and child care centers. Reports from providers and information gathered through sentinel surveillance will be important for monitoring changes in the epidemiology of this disease in Arizona. Please contact your local health department or the Arizona Department of Health Services Infectious Disease Epidemiology Section at 602.364.3676 if you have any questions about reporting varicella or need additional Communicable Disease Report forms. 2003 West Nile Wrap-Up In 2003, the State Health Lab tested approximately 2,100 mosquito samples, 1,200 chicken bloods and 200 human specimens. In addition, the University of Arizona Veterinary Diagnostic Lab tested more than 230 horses and 870 dead birds. As of Dec. 22, 2003, the following turned up positive for West Nile: 12 humans; 98 mosquito pools; 54 birds; 26 sentinel chickens; and 111 horses. A tremendous amount of teamwork occurred between the state, tribal and county health departments, as well as the University of Arizona Diagnostic Lab, State Health Laboratory, Arizona Dept of Agriculture, Arizona Game and Fish, Yuma County Pest Abatement District, Navajo Veterinary Service, Indian Health Services, many large animal veterinarians, and others for the bounty of surveillance data gathered this year. To bolster the state’s West Nile virus surveillance efforts, the Arizona Department of Health Services issued an emergency order in August making West Nile virus a reportable disease. Under the order, a physician or an administrator of a health care facility is required to submit a communicable disease report of a case or a suspect case of West Nile within 24 hours of diagnosis to the local health agency. Additionally, clinical laboratories are required to report to the Department. For more information, contact your local health department or ADHS at 602.364.3851. SARS continued from page 2 On our end, that’s also a lot of reports that we will have to investigate, looking for clusters, particularly suspicious cases, and determining whether SARS testing may be appropriate. SARS testing is available at the State Lab, but there is a high false positive rate in a setting of little or no known disease. SARS testing will therefore be limited to patients with certain epidemiologic factors as determined case-by-case by the local health department. We have developed a SARS Reference Guide for local health departments, will have reporting rules in place, and we’re gearing up for a LOT of ruling-out. Does this make sense? Absolutely. SARS exploded within health care facilities that missed that first case, so high suspicion is warranted, within reason. We are of course unlikely to find the first case of a new outbreak before cases are found in Asia, so ask the right questions but keep your differential diagnosis in perspective. More importantly, perhaps, is that the emphasis on respiratory hygiene will go a long way to prevent the spread of all sorts of respiratory infections, and that should make life better for all of us. Bob England, MD, is the State Epidemiologist and can be reached at 602.364.3582 or benglan@hs.state.az.us. Prevention Bulletin 3 Medical Professionals: A Key Component of Substance Abuse Treatment As a chronic, life-threatening condition, substance abuse has extraordinarily negative effects on the health, behavior, and development of human beings. Substance abuse contributes to 100,000 deaths in the United States per year and costs society billions of dollars each year. Medical professionals are in a unique position to identify substance abuse problems in patients and initiate treatment early. Doctors, nurses, and physicians assistants are encouraged to screen patients for substance abuse as a part of inquiring about other lifestyle issues. If substance abuse is suspected, medical professionals should refer the patient to a licensed behavioral health provider for a thorough assessment and treatment. Because substance abuse exacerbates other medical conditions, medical professionals should screen for substance abuse whenever unusual symptoms are observed that may indicate substance abuse. Affordable treatment is available throughout Arizona for addiction treatment. Federal and State appropriations are passed down from the Division of Behavioral Health through Regional Behavioral Health Authorities (RBHAs) to providers for individuals enrolled in AHCCCS and other groups depending on funding availability. progress. Individuals addicted to alcohol • More Arizona teens smoke marijuana than tobacco. or other drugs often have co-occurring • 20% of Arizona high school students go to school physical health intoxicated. problems and • 10% of Arizona residents have a drug or alcohol injuries such as: problem. fractures, chronic • Senior citizens exhibit a high rate of alcohol abuse. pain, depression, • Illicit drug use in Arizona is increasing. anxiety, gastritis, high blood pressure, • Arizona’s rate of illicit drug use ranks among the sprains, strains, ten highest in the Nation. burns, headaches, • Most people addicted to substances cannot stop and arthritis. using them without help. Medical profession• Only 1/4 of the people who need treatment for als can instruct substance abuse receive it. patients in alternative methods to relieve pain, anxiety, and Providers strive to enhance supinsomnia such as: physical therapy, port systems through integration of relaxation methods, ice, heat, substance abuse treatment with massage, deep breathing, and/or community and family systems. As meditation. Medications a physician part of a new initiative, behavioral might normally prescribe for pain, health providers are developing or insomnia (such as narcotics) can treatment teams for each person in trigger relapse in patients with the behavioral health system. substance abuse disorders. This is Treatment teams are composed of why coordination of care between the client, persons the client identithe Primary Care Provider and the fies as family, and persons who have Substance Abuse Treatment Provider knowledge of or influence on the is essential. individual’s recovery. Regional Behavioral Health As a part of the team, medical Authorities (RBHAs) can recommend professionals treat medical condia substance abuse treatment facility tions, encourage continuing particiin your community. pation in behavioral health services, conduct follow up visits after treatment termination, and monitor continued on page 5 Facts About Substance Abuse in Arizona RBHA The EXCEL Group Community Partnership of Southern Arizona Phone Number 1.800.880.8901 1.800.771.9889 Pinal Gila Behavioral Health Authority Counties Served Yuma and La Paz Pima, Graham, Greenlee, Cochise, and Santa Cruz Maricopa Mohave, Coconino, Apache, Navajo, and Yavapai Pinal and Gila TRBHA Gila River Health Care Corporation Navajo Nation Pasqua Yaqui Tribe Served Gila River Indian Community Navajo Nation Pasqua Yacqui Phone Number 602.528.1343 928.871.6239 520.879.6060 Value Options Northern Arizona Regional Behavioral Health Authority 4 By Lisa Shumaker Prevention Bulletin 1.800.564.5465 1.800.640.2123 1.800.982.1317 January/February 2004 Substance Abuse continued from page 4 References Bureau of Substance Abuse and General Mental Health (1998). Substance Use in Arizona: Final Report of the 1996 Telephone Household Survey. Arizona Department of Health Services. Wright, Douglas (2003). State Estimates of Substance Use from the 2001 National Household Survey on Drug Abuse: Volume 1. Findings (DHHS Publication No. SMA 03-3775, NHSDA Series H-19) Rockville, MD: Substance Abuse and Mental Health Services Administration, Office of Applied Studies. Lisa Shumaker is a Community Program Representative in the ADHS Division of Behavioral Health Services. She can be reached at 602.364.4600 or lshumak@hs.state.az.us. Some Indicators of Substance Use • Consumes more than 4 alcoholic drinks at one time (men) at least once per month. • Consumes more than 3 alcoholic drinks at one time (women) at least once per month. • History of a problem with alcohol or other substances. National Alcohol Screening Day National Alcohol Screening Day (NASD) is a free annual event to raise awareness about alcohol’s effect on health and to screen for at-risk drinking. NASD is a ready-to-use education and screening program that explores alcohol effects on health and connects people in need with treatment. In-person trainings & web-based training are available to sites wishing to participate in NASD. NASD will take place on April 8, 2004. If you are an agency that would like to participate in NASD or for additional information, please contact Cora Bagley at 602.364.4612. • Neglects responsibilities due to binge drinking or drug use. • Prior hospitalization for drugs or alcohol. • History of taking prescription medications in inappropriate doses or combinations. • Spouse or significant other is concerned about the patients’ substance abuse. New State Health Laboratory Expected to Open in June 2004 The Arizona Department of Health Services new State Laboratory facility is under construction with expected completion and occupancy by June 2004. Much of the external construction has been completed. The remaining work involves completion of the installation of the chemical fume hoods, biological safety cabinets, autoclaves and laboratory casework. The state-of-the-art laboratory will contain approximately 75,000 gross square feet. The first floor will be administrative offices, training facilities, storage, mechanical systems and the loading dock for receipt of supplies and delivery of specimens. The second floor will house all of Microbiology; the third floor will be Chemistry. The laboratory will contain advanced security systems, communications and conferencing networks. A seminar/conference center will accommodate up to 100 people. This space can also be subdivided to host smaller presentations. A training laboratory has been included to host sessions of 16 students in laboratory procedures training ranging from Biological Safety Level III to less complex standard methodologies. The Design-Build Team of Gilbane Construction, CUH2A Architects, the Arizona Department of Administration and the Arizona Department of Health Services have collaborated to develop an extremely successful project. January/February 2004 Prevention Bulletin 5 SUMMARY OF SELECTED REPORTABLE DISEASES Year to Date (January - November, 2003)1, 2 Jan - Nov 2003 Jan - Nov 2002 5 Year Median Jan - Nov 7 (3) 1 0 79 (50) 0 (0) 6 (4) 0 1 221 (103) 0 (0) 6 (4) 1 2 213 (103) 0 (0) 791 39 10 737 531 671 36 16 711 564 584 36 16 725 553 271 286 935 7 8,533 (3,232) 286 226 1,040 6 9,460 (4,776) 432 169 960 11 5,671 (2,085) 504 146 21 14 709 281 24 31 708 188 38 31 12,121 3,352 170 (18) 13,569 3,385 172 (14) 11,624 3,800 175 (26) 6 (1) 713 9 (0) 944 9 (1) 879 0 0 70 1 0 137 3 0 95 2,430 199 493 431 273 (246) 2,724 204 449 388 223 (200) 1,773 197 449 455 259 (200) VACCINE PREVENTABLE DISEASES: Haemophilus influenzae, serotype b invasive disease (<5 years of age) Measles Mumps Pertussis (<12 years of age) Rubella (Congenital Rubella Syndrome) FOODBORNE DISEASES: Campylobacteriosis E.coli O157:H7 Listeriosis Salmonellosis Shigellosis VIRAL HEPATITIDES: Hepatitis A Hepatitis B: acute Hepatitis B: non-acute3 Hepatitis C: acute Hepatitis C: non-acute3 (confirmed to date) INVASIVE DISEASES: Streptococcus pneumoniae Streptococcus Group A Streptococcus Group B in infants <30 days of age Meningococcal Infection SEXUALLY TRANSMITTED DISEASES: Chlamydia Gonorrhea P/S Syphilis (Congenital Syphilis) DRUG-RESISTANT BACTERIA: TB isolates resistant to at least INH (resistant to at least INH & Rifampin) Vancomycin resistant Enterococci isolates VECTOR-BORNE & ZOONOTIC DISEASES: Hantavirus Pulmonary Syndrome Plague Animals with Rabies4 ALSO OF INTEREST IN ARIZONA: Coccidioidomycosis Tuberculosis HIV AIDS Lead Poisoning (<16 years of age) 1 2 3 4 6 Data are provisional and reflect case reports during this period except Lead Poisoning which is by date of diagnosis. These counts reflect the year reported or tested and not the date infected. Case counts for non-acute Hepatitis B and C are not available before 1998. Based on animals submitted for rabies testing. Prevention Bulletin January/February 2004 HIV and AIDS in the State of Arizona Since 1981, the first year of HIV/AIDS reporting in Arizona, a total of 8,785 AIDS cases and 5,545 cases of HIV(non-AIDS) were reported to the Arizona Department of Health Services. Of these, 53 percent of the AIDS cases and 9 percent of the HIV cases are deceased (See Figure 1). Cases of HIV and AIDS are distributed disproportionately in state metropolitan centers. Maricopa County, the state’s largest urban area, comprises 60 percent of Arizona’s population and 70 percent of the AIDS cases and 72 percent of the HIV cases. Pima County, the next most populous urban county with 16 percent of the state’s population, has 20 percent of the state’s AIDS cases and 19 percent of its HIV cases. The remaining cases, less than one-fourth of the total, are scattered across the rest of Arizona. Despite increases over the past ten years in heterosexual transmission, the primary risk factor in Arizona for HIV continues to be among men who have sex with men (MSM), followed by intravenous drug use (See Figure 2.). Overall reports of HIV infection have fallen during the decade between these time periods, from 1,902 during 1990-1992 to 1,405 during 2000-2002. For more information on HIV/AIDS, contact ADHS at 602.364.3610 or visit the web at www.hs.state.az.us. Figure 1 Figure 2 1990-1992 Modes of Exposure for Ten-Year Span of HIV Cases in Arizona 2000-2002 n=1,902 n=1,405 January/February 2004 Prevention Bulletin 7 ❍ Change of Address/Name ❍ Delete my name from your mailing list ❍ I received more than one copy Arizona Department of Health Services Public Information Office 150 North 18th Avenue Phoenix, AZ 85007 Please include your mailing label with all requests for changes. Fax changes to 602.542.1265 or call 602.364.2401 PRSRT STD US Postage PAID Phoenix, AZ Permit No. 957 Janet Napolitano, Governor Catherine R. Eden, Ph.D., Director ADHS Rose Conner, Assistant Director, Public Health Services Editorial Board Bob England, M.D., M.P.H., State Epidemiologist Victorio Vaz, D.V.M., Ph.D. Tim Flood, M.D. Kathy Fredrickson, M.P.H. Will Humble, M.P.H. Karen Lewis, M.D. Ken Komatsu, M.P.H. Cheryl McRill, M.D. Wesley Press, M.S. Lisa Shumaker, M.A. Emma N. Viera, M.P.H. Managing Editor: Courtney Casillas e-mail: ccasill@hs.state.az.us Contributors: Bob England, Laura Erhart, Mersija Hadzihasanovic, Sarah Harpring, Karen Lewis, Lisa Shumaker This publication is supported by the Preventive Health and Health Services Block Grant from the Centers for Disease Control and Prevention (CDC). Its contents do not necessarily represent the views of the CDC. If you need this publication in alternative format, please contact the ADHS Public Information Office at 602.364.1201 or 1.800.367.8939 (State TDD/TTY Relay). New Communicable Disease Rules Published Proposed revisions to the communicable disease rules in 9 A.A.C. 6, Articles 1, 2, 3, 5, and 6 will be published in the Arizona Administrative Register on January 9, 2004. The Notice of Proposed Rulemaking is the result of a lengthy rule drafting process during which the Bureau of Epidemiology and Disease Control Services (BEDCS) solicited and obtained input from interested persons starting in March 2003. In preparing the proposed rules, BEDCS seriously considered each of the comments received and made numerous changes in response to those comments. BEDCS believes that the proposed rules reflect the best means to improve Arizona’s system for detecting, reporting, controlling, and preventing communicable diseases and thereby to protect and improve the public health. 8 Prevention Bulletin BEDCS will be holding three oral proceedings (in Phoenix, Flagstaff, and Tucson) to obtain public comment on the proposed rules: February 9, 2004; 1:00 p.m. 1740 W. Adams, Room 411 Phoenix, AZ 85007 February 10, 2004; 1:00 p.m 1500 E. Cedar Ave., Suite 22 Flagstaff, AZ 86004 February 11, 2004; 1:00 p.m 400 W. Congress Room 5 Tucson, AZ 85701 Written comments may also be submitted, until 5:00 p.m. on February 13, 2004, to the individuals identified in the Notice of Proposed Rulemaking. On January 9, 2004, the Notice of Proposed Rulemaking will be available for review on the ADHS website by going to www.hs.state. az.us/diro/admin_rules/proposed.htm and selecting the link for “Communicable Diseases and Infestations” under Division of Public Health Services. If you do not have access to the ADHS website and would like a copy of the proposed rules, please call 602.364.0781 to request a copy. January/February 2004