STATE OF ARIZONA SILVER CREEKSUBDMSION TUCSON, PIMA COUNTY, ARIZONA JUNE 3, 2005 u.s. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service Agency for Toxic Substancesand DiseaseRegistry Division of Health Assessmentand Consultation Atlanta, Georgia 30333 Health Consultation: A Note of Explanation An ATSDR health consultation is a verbal or written response from ATSDR to a specific request for information about health risks related to a specific site, a chemical release, or the presence of hazardous material. In order to prevent or mitigate exposures, a consultation may lead to specific actions, such as restricting use of or replacing water supplies; intensifying environmental sampling; restricting site access; or removing the contaminatedmaterial. hI addition, consultationsmay recommendadditional public health actions, such as conductinghealthsurveillanceactivitiesto evaluateexposureor trendsin adversehealth outcomes;conductingbiological indicatorsof exposurestudiesto assessexposure;and providing health education for health care providers and community members. This concludesthe health consultationprocessfor this site, unlessadditional information is obtainedby ATSDRwhich, in the Agency'sopinion,indicatesa needto revise or append the conclusionspreviouslyissued. You May ContactA TSDR TOLL FREE at 1-888-42ATSDR or Visit our HomePageat: http://www.atsdr.cdc.gov HEALTH CONSULTATION STATE OF ARIZONA SILVER CREEK SUBDIVISION TUCSON, PllvIA COUNTY, ARIZONA Prepared by: u.s. Departmentof HealthandHumanServices Agencyfor Toxic Substances andDiseaseRegistry Division of HealthAssessment and Consultation Purpose The Arizona Department of Health Services (ADHS) completed this health consultation at the request of the Arizona Department of Environmental Quality (ADEQ). This consult evaluateswhether soil vapors from volatile organic compoundsin the subsurface near the Silver Creek Subdivision in Tucson, Arizona are present at levels that may cause adversehealth effects. Background The Silver Creek subdivision is located approximately 4 miles northwest of downtown Tucson. Approximately 700 residentslive in the 288 home subdivision. A gasoline releasefrom a ruptured high-pressurepipeline occurred in the Silvercroft Wash near the Silver Creek subdivision on July 20, 2003. Over 50,000 gallons of gasoline have been recovered from the subsurface. Five homes under construction in the areawere demolished following the pipeline rupture becauseof gasoline contamination. The homes in this portion of the subdivision have not beenrebuilt. Levine Fricke (LFR) on behalf of pipeline owner Kinder Morgan Energy Partners (KMEP) perfomled a soil vapor survey as part of the Silvercroft Wash Fuel Releasesite assessmentand remediation project. In addition to total petroleumhydrocarbons (TPH) and their related compounds (benzene,toluene, ethylbenzene,and xylenes [BTEX], methyl-t-butyl ether [MTBED, LFR sampling detectednon-fuel related chlorinated solvents, such as tetrachloroethene (PCE) and tricWoroethene(TCE) in soil vapor and groundwatersamples beneaththe study area. As the study focused only on fuel-related volatile organic compounds, it did not fully evaluatethe extent of the non-fuel related volatile organic compounds. The Arizona Departmentof Environmental Quality conductedadditional soil vapor sampling to obtain analytical soil vapor data to independentlyverify and expand upon soil vapor data collected by Levine Fricke. ExposurePathways Five elementsareconsideredin the evaluationof exposure pathways: A sourceof contamination Transportthroughan environmentalmedium A point of exposure Exposureroute A receptorpopulation. The Arizona Department of Health Servicescategorizesan exposurepathway either as "completed" or as a "potential" exposurepathway if the pathway cannotbe eliminated. In completed exposurepathways, all five elementsexist, and exposureto a contaminant has occurred in the past, is presently occurring, or will occur in-the future. In potential exposurepathways, at leastone of the five elementsis missing but could exist. Potential pathways indicate that exposureto a contaminantcould have occurred in 1 . .. .. the past, or may occur in the future. A potential exposurepathway may be eliminated if one of the five elements is missing and is unlikely ever to be present. Vapor intrusion and inhalation of those vapors is a potentially complete exposure pathway. Soil vapor intrusion refers to the migration of volatile chemicals from the subsurfaceinto overlying buildings. Volatile chemicals in contaminated soils, buried wastes and/or contaminated groundwater can emit vapors that may migrate through subsurfacesoils and into indoor air spacesof overlying buildings similar to the seepage of radon gas into homes. Residentsare likely to be exposedto the soil vapors that migrate into homes in the Silver Creek neighborhood resulting in a completed exposurepathway. ADEQ Flux Chamber Sampling -Silver Creek Subdivision The Arizona Department of Environmental Quality conductedadditional soil vapor sampling to evaluate the potential public health impact to the residents of the Silver Creek subdivision from vapors detectedpreviously during investigation of Silvercroft WashFuel Release. The Arizona Department of Environmental Quality collected soil vapor samples by placing a flux chamber over open soil and on concrete. The data set available for this health consultation is limited to the results of environmental.samplescollected at 60 flux chamberssamplescollected at a fixed point in time. One of the flux chamberswas set up directly adjacentto the pipeline where no homes are presentand was excluded from the database. In addition, there were 2 background samplesthat were collected but excluded from the databasebecausethey are not specific to the neighborhood. Data from a total of 57 flux chamberswere used in this health consultation. An extensive list of target contaminants,including volatile organic compounds not associatedwith gasoline was evaluated.The results of the evaluation found elevated concentrationsof compounds that are consistent with materials that have been previously detectedat and near known sources in the area as well as compounds that may be associatedwith the gasoline pipeline release. The results from the flux chamberssampleswere used to estimate indoor air concentrationsusing standardbox models (SECOR 2005). The models provide a conservativeestimate of predicted indoor air concentrations.This formula takes into accountthe mobility of the contaminantsand use factorsdesignedto result in the highest (and thus most protective) concentrationestimatesof contaminants in the air. The following expressionsdisplay the model equations and assumptionsused to calculate predicted indoor air concentration at both the open soil and concrete slab sampling locations: 2 Open Soil Flux Chamber Expression: Cair = Fj x SA x CL x CF AERxV Where: Cair - Fi SA CL CF AER V hldoor air concentration in micrograms per cubic meter (~g/m3) Site specific hlfiltration flux, in micrograms per feet a minute (~g/ft-min) Surface Area Perimeter, 144square meters (m2) Crack level, estimatedto be 0.01 (unitless) (ASTM 1997) Conversion factor 60 minutes per hour; Air exchangerate, assumedat 0.25 hour-1(USEPA 2003) Average volume of residential structure, assumed351 cubic meters (m3) estimated for a home measuring 12 meters (m) by 12 meters (m) and a ceiling height of2.44 meters (m) Concrete Slab Flux ChamberExpression: Cair= Fi x P x CFl~CF2. AERxV Where: Cair Fj P CF1 CF2 AER V - Indoor air concentration in micrograms per cubic meter (J.1g/m3) Site specific Infiltration flux, in micrograms per feet a minute (J.1g/ft-min) Perimeter, 48 meters (m) Conversion factor 1, 0.3 feet per minute (ft/m) Conversion factor 2, 60 minutes per "hour Air exchangerate, assumedat 0.25 hour-1(USEPA 2003) Average volume of residential structure, assumed351 cubic meters (m3) for a home measuring 12 meters (m) by 12 meters (m) and a ceiling height of 2.44 meters (m). Modeling results for each flux chamberare available in the documententitled Soil Vapor Sampling Report, Silver CreekSubdivision. (SECOR 2005) Risk Analysis Contaminantsof Concern (CaCs) were evaluated for systemic toxicity and carcinogenicity. Systemic toxicity refers to the potential for a compound to causeeither symptomatic or asymptomatic health problems in humans. Carcinogenicity refers to the potential for compoundsto causecancerin humans. Systemic Toxicity The Arizona Department of Health Servicesselectedcontaminantsof concernby comparing the averagepredicted indoor air concentrationsto the Agency for Toxic Substancesand Disease Registry (ATSDR) ComparisonValues (CVs) and the United StatesEnvironmental Protection Agency (USEPA) ReferenceConcentrations(RfC). The flux chambersampleswere used to predict indoor air concentrationsby applying conservativeassumptionsthat provide an upper-bound estimate of actual indoor air concentrations. These modeledresults representconditions observedon the days samples 3 I were collected and do not predict potential variations in contaminantconcentrations that may occur over time. The Arizona Departmentof HealthServicesselectedthe contaminantsof concernby averagingthepredictedindoor air concentrationsand comparingthe resulting concentrations to screeninglevels. Compoundswere selectedasa contaminantof concernif thepredictedaverageconcentrationexceededa screeninglevel. The averageindoor air concentrations, rather than the maximum indoor air concentrations,were chosen for comparison with the screeninglevels to optimize the limited datasetavailable from this single sampling event, to provide a broader statistical baseto make comparisons,and to provide a better benchmark for drawing conclusions for the entire neighborhood. The primary screeninglevels that were used to select contaIninantsof concern are called Air ComparisonValues (CVs). These screeninglevels are concentrations in air that are unlikely to pose a health threat. Where the air comparison values were not available for a specific compound, the modeled results were compared to the United States Environmental Protection Agency's ReferenceConcentration (RfC) or preliminary remediation goals (pRGs). The air reference concentrations and the preliminary remediation goals are applicable to both indoor and outdoor air and are based on a residential exposurescenario using standardexposure factors. These screening levels may also be used as a health protective indoor air target for determining soil gas screeninglevels for the evaluation of the subsurface vapor intrusion pathway (ATSDR 2005). Arizona Ambient Air Quality Guidelines were us,edas screeninglevels when no comparisonvalues,reference concentrations or preliminary remediation goals were available. Theseguidelines are developed by the Arizona Department of Health Services, and are protective of human health, including children, over a lifetime. Chemical concentrationsin air that exceed any of these guidelines may not necessarilyrepresenta health risk (AAAQG 1999). Predicted indoor air concentrations that exceeda screening criteria do not necessarily pose a health threat, but require further evaluation. Table 1. Predicted Indoor Air ConcentrationsCompared to ScreeningValues Average dOc'"": ""Rre I..~~~d Frequency" Compound Health c' "fn~oQi~jr~ Air Concentration Eff~ct "Concentration ,Screening Detect~d , ", , .. Value" (n=57') (fi§Jfu3) , Chemica]of ~v~rageAbove Concern.? Scr~~ning VariJe? meter(l.J;9!m~)" c" Acetone 1 0.51 Acrylonitrile 7 0.06 Allyl chloride 6 0.06 Benzene 32 Benzyl chloride 8 0 0.47 0.11 0 Bromodichloromethane 4 ~ 13000~ i 22I 1;j 37.r O2 na5 - No No No No No No No No No No No No Average Predicted: Compound Freguency Indoor Air Detected Concentration . (n=57) (micrograms per cubic meter 3 5 0 24 18 19 0 5 6 27 4 0 5 0 5 6 4 7 47 0 5 0 0 22 1 1 0 0 11 0 5 5 14 12 0 4 7 17 8 57 1 0 20 3 I Health Effect! Air Concentration ScreeningI ValueI Average Above Screening Chemical of Concern? Value? (~g/m3) (!-1g/m3) 0.16 0.03 0 0.06 0.24 0.02 0 0.08 0.03 0.04 0.12 0 1./ ~ na 50002 ~-1951 ~ ~ na 21 na 0.25 0.07 0.12 0.83 0.06 0.13 92 0.12 0.18 9.06 0.14 5 No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No 1~ na1000Q2 0.21 0 0.18 0.14 0.15 0.08 0.03 0.02 0.06 0.06 2.70 0.08 0.08 0 0 0.03 0 0.03 0.16 0.11 0.04 No No No No No na -92 -~ 6001 ~ na 6001 -~ -.:?:Q~ 4.13-~ na na na-21 3001 No No No No No 310003 No No na No No No No No No No No No No No No No No No No na 202 10002 35002 0.863 403 15003 No :~~r~No No na na 30002 1104 No No No No -~ ~ I Frequency .' .' Compound Detected (n=57) AverageI PredictedI Indoor Air Concentration (micrograms per cubic meter (~g'm3) Methyl ten butyl ether 6 Methylstyrene 6 Napthalene Octane 18 21 Propionitrile 7 7 2 6 7 Trimethylbenzene 36 Trimethylbenzene .vinyl acetate 22 14 0.21 Tetrachloroethane Tetrachloroethane Tetrachloroethene 1,2,4 1,1,2 1,1,1 1,2,3 _J!2,4 ~ 0- 0.46 0.10 0.07 0.08 0.10 0.15 0.08 0.86 1.48 0.04 0.03 0.03 0.06 0.11 0.19 0.11 Styrene 1,1,1,2 1,1 ,2,2 11.31 0.10 Toluene Trichlorobenzene Trichloroethane Trichloroethane 10 Trichloroethene 1 Trichlorofluoromethane 30 I rlCnloropropane 6 5 0 3 Health Effect Air Concentration...Chemical of Average Above Screening Value 3 (/-lg/m ) No No 424 3.51 .:!J.§~ 2401 ~ 401 ~ 3204 Na 7001 na 562002~~ 6.23 6.23 ~- 0 0 na Xylene 5 0.62 4351 Xylene 5 0.19 ~ No No No No No No No 2581 ~- Vinyl chloride Screening Value? No No No No No Concern? No No No No No No No No No No No No No No No No No No No No No No No No No No No No No No I ATSDR EMEG 2EPA Reference Concentration 3EPA Region 9 Preliminary Remediation Goal 4Arizona Ambient Air Quality Value 5No screening value available (na) 6 Simple asphyxiant value is the Lower Explosive Limit As shown in Table 1, no chemicals of concernwere selected for further analysis, indicating that for all of the compounds,predicted indoor air concentrationsin the neighborhood do not pose a systemic health hazard. Carcinogenicity Carcinogepic risk is calculated as the incremental probability of an individual developing cancerover a lifetime (70 years), due to exposureto a carcinogenic compound. This is also referred to as incremental or excesslifetime cancerrisk (ELCR) and representsthe increasedrisk of developing cancerabQvethe background rate, which is estimated to be about33%. While the criteria for selecting the contaminantsof concern for cancerare the same as with the systemic health effects, predicted indoor air concentrationsare compared to a different set of air comparison values. The guidelines used for this selection are also from the Agency for Toxic Substancesand DiseaseRegeistry's air comparisonvalues, but are 6 values used to screencontaminants that are suspectedof causing cancer.These guidelines are known as cancerrisk evaluation guides (CREGs). If there are no cancerrisk evaluation guides for contaminants, then the U.S. Environmental Protection Agency's CancerPreliminary Remediation Goal is used to detennine if more evaluation is warranted. The contaminantsof concernwere selectedby comparing the averagepredicted indoor air concentrationsto the air comparisonvalues. Contaminantsof concern were selectedfor further analysis if the averagepredicted indoor air concentrationexceededits screeninglevel. Table 2 displays a list of all suspectedcarcinogensobserved in the sampling and their screeningvalue. Table2. PredictedIndoor Air ConcentrationsComparedto CancerScreeningValues Compound Air Ayerage Concentration rrequ~~cy Predicted CancerScreenina Chemical Average Air Detected' Indoor ,Concentration! of IConcern? (11=511 I 3 ,Hgm ) I !c'" 7 0.06 0.06 0.47 0 0.16 0 0.02 0.08 0.03 0 0.12 0.15 0.02 2.70 0.08 0.03 0.03 0.83 0.46 0.10 0.15 0.03 0.04 0.03 0 6 32 0 3 0 1-9 5: 6 0 4 7 5 22 1 11 5 7 18 2 6 7 5 1 0 Above Value 1 I (""91m3) 0.01' 31 0.11 0.112 M1 Q'Q31 -ow 2]2 0]41 b:oar 0.0034 ~ Q]'4;l -31 --ow ~ ~ 0.31 -~ ~ ow~ ~ o:o1r ~ Screening Value? Yes No Yes No No No No No No No Yes No No No No No No Yes Yes No Yes No No Yes No A TSDR Cancer Risk Evaluation Guideline 2USEr A Region 9 Preliminary Remediation Goal There were 7 contaminantswith an averagepredicted indoor air concentrationthat exceededthe screeninglevels. Table 3 summarizesthese7 contaminants. 7 Yes No Yes No No No No No No No Yes No No No No No No Yes Yes No Yes No No Yes No Table 3. Suspectedcarcinogeniccontaminantsdetectedabovethe screeninglevels lAveragePredictedI Compound Frequency Detectedi' (n=57) 7 32 4 7 1..2 18 6 Trichloroethene I rh~OorA!r Cpncentration (pglm3) ., 0.06 0.47 0.12 0.83 0.46 0.15 0.03 Cancer Screening Value (~g/m3) 0:01' Yes Qm1 Yes Yes 0.0034 Yes ~"'0m2-Q"i)2T Yes Yes Yes 0:0172 ~ Yes Yes Yes Yes Yes Yes Yes 'ATSDR Cancer Risk Evaluation Guideline 2USEPA Region 9 Prelirnmary Remediation Goal Using the list of contaminants of concern,estimatesof estimated lifetime cancer risk were developed by evaluating potential exposurepathways, estimating exposure concentrationsand intake, and combining exposure estimateswith toxicology information (USEPA 1991). The dose-responserelationship is consideredto be linear under the low dose conditions usually encounteredin environmental exposures. Under this assumption,the US Environmental Protection Agency slope factor (SF) for a compound is a constant, and risk is directly related to intake. Therefore, the linear low-dose cancer risk is: Risk = Cancer Inhalation Unit Risk (l/J.lglm3) x Concentration (J.lglm3) where: Risk Unit Risk Concentration a unitless probability of an individual developing cancer; Dose averaged over 70 years (1/J.l.glm3) (USEPA 2005); and Predicted indoor air concentration (J.l.glm3). Table 4 summarizesestimatedlifetime cancer risk using averagepredicted indoor air concentrations. Cancerinhalation unit risk is the upper-bound excesslifetime cancerrisk estimatedto result from continuous exposureto a compound at a concentration1 ~g/m3 in air. The unit risk values are developedby the US Environmental Protection Agency after careful and detailed analysesof data regarding the potential cancerpotency of a compound. 8 AcrylonitrileBenzeneDibromoethaneHexachlorobutadieneNapthaleneTetrachloroethane ~ ;::U! Table4. EstimatedExcessCancerRisk otal Excess Lifetime Cancer Risk 0.00007 Micrograms per cubic meter of air 2 Source: (USEPA 2005) 3 Average Air Concentration X Unit Risk The estimatedupper-boundexcesscancerrisk estimate of 0.00007 or seven-in-onehundred-thousandrepresentsthe increasedrisk of developing cancer. This estimatewas calculated by multiplying averagepredicted contaminant concentrationsby the Unit Risk. There is general(although not unanimous)consensusanlong the scientific and regulatory communities on what level of estimatedexcesscancer risk is acceptable. An increased lifetime cancerrisk of one in one million or less is generally considerednegligible. According to the United StatesEnvironmental Protection Agency National Contingency Plan and subsequentguidance,an estimateof excess cancerrisk betweenone in a million to less and one in ten thousandis within a range of acceptablerisk (USEPA 1990, 1991). Risks greaterthan one in ten thousanddo not necessarilypose a significant cancerrisk, but require additional in-depth analysis in order to draw conclusions about potential cancerrisk. The upper-boundestimatedrisk from indoor infiltration of contaminantsis within the range of acceptablerisk and posesno apparentpublic health hazard to neighborhood residents. Limitations There are many sourcesof uncertainty in every risk analysis. The objective of this health consultationis to determine whether soil vapors from compounds in the subsurfacenear the Silver Creek Subdivision in Tucson, Arizona are present at levels that may cause adversehealth effects. This health consultation is a screeninglevel analysis of health risks, meaning that the report usesa conservative (or upper-bound)analysis. Severalconservativeassumptionswere made in this analysis. Infiltration into neighborhoodhomeswas assumedto be a complete exposurepathway even though this pathway may not actually be complete. Compounds that were detectedin flux chambers at levels less than the reporting limits (called J Flagged Data -meaning that they were qualitatively but not quantitatively accuratelyidentified) were still included in the databaseto ensurethat no compoundswere left out of the analysis. The screeninglevels that were usedto selectcontaminantsof concernhave a large margin of safety. The 9 . exposureassumptionsusedto developthe screening levels assumecontinuous 30-year exposureaveragedover a 70-year lifetime. Finally, the US Environmental Protection Agency unit risk values usedto calculate cancer risk are upper-bound estimatesthat almost certainly overestimaterisk. \ The average air concentrationsused in this health consultation are estimatesbased on flux chamber air sampling data collected at the site. The results were used to estimate indoor air concentrations. The air concentrations used in this health consultation' representenvironmental conditions at one point in time. Ideally, for where vapor intrusion is a concern, pennanentsub-surfacemonitoring points for sample collection would be used to evaluate the long-tenn behavior of soil vapors. In addition, it may be necessaryto collect soil gassamples at different time intervals to compensatefor the effects of weatherevents, suchas recentrainfall or barometric fluctuations (DTSC 2004). Child Health Issues The Agency for Toxic Substancesand Disease Registry recognizes that the unique vulnerabilities of infants and children demand special emphasis in communities faced with contaminantsin air. Children's developing body systemscan sustain permanent damageif toxic exposuresoccur during critical growth stages.Children breathe a greater volume of air relative to body weight, resulting in higher burden of pollutants. Furthermore,children, eventhose without pre-existing illness or chronic conditions, are susceptibleto air pollution becausetheir lungs are still developing, and they often engage in vigorous outdoor activities, making them more sensitive to pollution than healthy adults. All calculations and health analysesin this report take into considerationthe unique vulnerability of children. -' Conclusion The predicted indoor air concentrations in Silver Creek neighborhood suggestthat the subsurfacecontaminantspose no apparent public health hazard. Recommendations The Arizona Department of Health Serviceshas no recommendationsat this time. 10 11 References AAAQG 1999. Arizona Annual Air Quality Guidelines. Arizona Departmentof Health Services.May, 1999. ASTM 1997. American Society for Testing and Materials. StandardGuide for Risk-based Corrective Action Applied at PetroleumReleaseSites. E 1739-95. 1997 ATSDR1995. Agencyfor Toxic Substances andDiseaseRegistry,ToxFAQsfor Hexachlorobutadiene. September 1995. ATSDR 2005. Agency for Toxic Substancesand DiseaseRegistry, Air ComparisonValues January2005 DTSC.2004. VaporIntrusionGuidanceDocument.Stateof California.DTSC/CAL EPA. December15,20-4. NIST/SEMATECH e-Handbookof Statistical Methods, ht!Q://www.itl.nist.gov/div898/handbook/. March 3, 2005. USEPA 1990. USEPA National Oil and HazardousSubstancesPollution Contingency Plan (NCP), 40 CFR Part 300, July 16, 1982 (47 FR 31180) and comprehensiverevision March 8, 1990 (55 FR 8666) http://www.epa.gov/superfund/sites/nDl/f900830.htm USEPA 1991. Risk AssessmentGuidance for Superfund (RAGS), Supplemental GuidanceStandardDefault Exposure Factors (OSWER Directive, 9285.6-03) dated March 25, 1991. USEPA 1992. Technology Transfer Network Air Toxics Website. Hexachlorobutadeine. httQ://www.eDa.gov/ttnatw01/hlthef/hexa-but.html.March 3, 2005. USEPA 2003. User Guide for Johnsonand Ettinger Model. USEPA 2005. Integrated Risk Infoffilation System. Online service at: htiD://www .epa.gov/iris/ SECOR2005. Soil Vapor Sampling Report. Silver Creek Subdivision, Silverbell Landfill Water Quality Assurance.February2005. Preparers of Report Arizona Department of Health Services, Office of Environmental Health KristinaSchaller,EnvironmentalHealthScientist DonHerrington,PrincipleInvestigator Will Humble,BureauChief Certification This Silver Creek Subdivision Public Health Consultationwas prepared by the Arizona Departmentof Health Services under a cooperative agreementwith the federal Agency for Toxic Substancesand DiseaseRegistry (ATSDR). It was completed in accordance with approvedmethodologies and proceduresexisting at the time the health consultation was initiated. Editorial review was completed by the Cooperative Agreementpartner. ;:JJ/J/l~ ~~ss1f~ {tP Technical Project Officer, CAT, SPAB, DHAC